Amicon Ultra Centrifugal Filters, 3 kDa Ultracel, 0.5 mL; 24/Pk

The low-binding ultracel-YM regenerated cellulose membrane, available with different molecular weight cut-offs, is ideal for dilute (ng/mL to µg/mL range) protein solutions. These devices are used in standard 1.5 mL tube fixed-angle rotors and have a wide range of applications, including concentrating and purifying proteins, antibodies, and nucleic acids (as an alternative to ethanol precipitation), desalting and buffer exchange, and the removal of primers, linkers, and unincorporated labels.

The maximum initial sample volume for these devices is 500 µl, and the typical final concentrate volume is 5 to 15 µl. The maximum centrifugal force is 14,000g, with a lower force of 500g for the 29950-54 devices used in DNA/RNA applications.

These membrane-based concentrators provide a convenient and efficient way to handle a variety of biomolecular samples. The low-binding properties of the regenerated cellulose membrane help to minimize sample loss, ensuring the recovery of valuable materials. The adjustable molecular weight cut-offs allow users to tailor the device selection to their specific sample requirements, enabling effective concentration and purification.

The fixed-angle rotor design of the 1.5 mL tube format ensures easy integration into standard laboratory centrifugation workflows, making these devices a versatile tool for researchers working with dilute protein, antibody, or nucleic acid samples. The ability to achieve significant volume reduction while maintaining sample integrity is a key advantage of these membrane-based concentrators, making them a valuable addition to the toolbox of any laboratory engaged in protein, antibody, or nucleic acid research and development.

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